发明名称 PROCESS FOR MANUFACTURING ORGANISED COLLAGEN STRUCTURES, PARTICULARLY OF HUMAN ORIGIN, AND ORGANISED COLLAGEN STRUCTURES CORRESPONDING THERETO
摘要 These organised structures may be either fibres or membranes. According to this process, a sample of animal or human tissue, washed and asepticised beforehand, is ground in a saline solution to solubilise the collagen present in the said sample. A catalyst for reconstituting the collagen fibres is then added to the extract obtained, consisting of collagen fibrils in a minimum quantity and free from nonfibrillar collagen precipitate. After a maturing stage the reconstituted organised structures are separated from the aqueous medium by centrifuging, are washed, asepticised, packaged, freeze- dried and sterilised. Among the organised structures obtained the collagen fibres are in the isolated state, separated from their original cell tissue, in the form of a network (35) and ready for use. They exhibit a periodicity of transverse striations (37) of between 68 nm and 72 nm. <IMAGE>
申请公布号 AU1859988(A) 申请公布日期 1989.01.05
申请号 AU19880018599 申请日期 1988.07.01
申请人 DIATECH LTD. 发明人 ISRAEL GOLDSTEIN
分类号 A61F2/10;A61F2/00;A61L15/40;A61L27/00;A61L27/24;C07K14/00;C08H1/00;C08H1/06;C08L89/06;D01F4/00 主分类号 A61F2/10
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