Monoclonal antibodies that bind and inhibit activation of epidermal growth factor receptor related member ErbB3/HER3 are disclosed. The antibodies can be used to treat cell proliferative diseases and disorders, including certain forms of cancer, associated with activation of ErbB3/HER3.
申请公布号
US2016264679(A1)
申请公布日期
2016.09.15
申请号
US201614987374
申请日期
2016.01.04
申请人
AVEO Pharmaceuticals, Inc.
发明人
Vincent Sylvie;Winston, JR. William M.;Wang Fang;Weiler Solly;Meetze Kristan;Breault Lyne;Bottega Steve;Chen Ting;DePrima Michael;Fleet Christina;Tyler Steven;Woo Jin-Kyeung;Gyuris Jeno
