| 发明名称 |
METHODS AND PHARMACEUTICAL COMPOSITIONS FOR MODULATING AUTOPHAGY IN A SUBJECT IN NEED THEREOF |
| 摘要 |
The present invention provides novel methods for the modulation of autophagy and the treatment of autophagy-related diseases, including cancer, neurodegenerative diseases, liver diseases, muscle diseases and pancreatitis. |
| 申请公布号 |
US2016250249(A1) |
申请公布日期 |
2016.09.01 |
| 申请号 |
US201415026986 |
申请日期 |
2014.10.03 |
| 申请人 |
INSERM ( INSTITUTE NATIONAL DE LASANTÉ ET DE LA RE CHERCHE MÉDICALE) ;ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS (APHP) ;UNIVERSITE PARIS DESCARTES ;UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) ;UNIVERSITE PARIS DIDEROT - PARIS 7 ;UNIVERSITE PARIS-SUD ;INSTITUT GUSTAVE ROUSSY |
发明人 |
KROEMER Guido;MARINO Guillermo;PIETROCOLA Federico |
| 分类号 |
A61K31/7076;A61K31/4458;A61K31/235;A61K45/06;A61K31/4155;A61K31/22;A61K31/385;A61K31/19;A61K31/405;A61K31/225 |
主分类号 |
A61K31/7076 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of inducing autophagy in a subject comprising administering the subject with an amount of at least one AcCoA depleting agent. |
| 地址 |
Paris FR |
