<p>Benzodiazepine derivatives are disclosed that act as potent inhibitors of ras farnesyl:protein transferase. Pharmaceutical compositions containing these benzodiazepines are provided for treatment of diseases for which inhibition of the ras farnesyl:protein transferase is indicated.</p>
申请公布号
EP0763537(A2)
申请公布日期
1997.03.19
申请号
EP19960118160
申请日期
1994.05.10
申请人
GENENTECH, INC.;BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM
发明人
MARSTERS, JAMES C., JR.;BROWN, MICHAEL S.;CROWLEY, CRAIG W.;GOLDSTEIN, JOSEPH L.;JAMES, GUY L.;MCDOWELL, ROBERT S.;OARE, DAVID;RAWSON, THOMAS E.;REYNOLDS, MARK