发明名称 Non-peptidyl Ras farnesyl transferase inhibitors
摘要 <p>Benzodiazepine derivatives are disclosed that act as potent inhibitors of ras farnesyl:protein transferase. Pharmaceutical compositions containing these benzodiazepines are provided for treatment of diseases for which inhibition of the ras farnesyl:protein transferase is indicated.</p>
申请公布号 EP0763537(A2) 申请公布日期 1997.03.19
申请号 EP19960118160 申请日期 1994.05.10
申请人 GENENTECH, INC.;BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM 发明人 MARSTERS, JAMES C., JR.;BROWN, MICHAEL S.;CROWLEY, CRAIG W.;GOLDSTEIN, JOSEPH L.;JAMES, GUY L.;MCDOWELL, ROBERT S.;OARE, DAVID;RAWSON, THOMAS E.;REYNOLDS, MARK
分类号 A61K31/55;A61K31/551;A61K38/00;A61P31/04;A61P35/00;C07D223/16;C07D243/10;C07D243/14;C07D243/24;C07D401/06;C07D401/14;C07D403/04;C07D403/06;C07D403/10;C07D403/12;C07D403/14;C07D405/06;C07D409/06;C07D409/14;C07D417/12;C07D417/14;C07D487/04;C07D498/04;C07D513/04;C07K5/02;C07K5/06;C07K5/078;C07K5/08;C07K5/083;C07K5/097;C07K5/10;C07K5/103;C07K5/117;(IPC1-7):C07D487/04;A61K31/425;A61K31/41;A61K31/42 主分类号 A61K31/55
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