| 发明名称 |
Methods of modulating of angiogenesis |
| 摘要 |
A method of inhibiting angiogenesis in a mammal by administering to the mammal a compound which inhibits binding of endothelial PAS domain protein-1 to cis-acting transcription regulatory sequence in the promoter region of a gene encoding an angiogenic factor.
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| 申请公布号 |
US6395548(B1) |
申请公布日期 |
2002.05.28 |
| 申请号 |
US19990374454 |
申请日期 |
1999.08.13 |
| 申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
LEE MU-EN;MAEMURA KOJI;HSIEH CHUNG-MING |
| 分类号 |
A61K38/00;C07K14/47;C07K16/18;C12N;G06F17/30;(IPC1-7):C12N15/09;C12N5/00;C12N15/63;C07H21/04 |
主分类号 |
A61K38/00 |
| 代理机构 |
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