METHOD FOR PRODUCING AZIDE SUGAR BY MICROORGANISM REACTION AND ENZYME REACTION

摘要

PROBLEM TO BE SOLVED: To provide a bacterium that belongs to the genus Klebsiella and has ability of producing L-tagatose from galactitol.

SOLUTION: The bacterium of the genus Klebsiella has ability of using 6-azide hexitol as a raw material in which the 6-position of hexose is azidated, oxidizing the 2-position and forming 6-azide ketohexose. Moreover, the bacterium of the genus Klebsiella has ability of isomerizing 6-azide ketohexose and producing 6-azide aldohexose. The 6-azide polyol dehydrogenase is produced by the bacterium, acts on 6-azide polyol and oxidizes the 2-position to give ketose so as to form 6-azide ketohexose. The 6-azide aldose isomerase isomerizes 6-azide ketohexose to produce 6-azide aldohexose.

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