SYNTHESES AND PREPARATIONS OF NARWEDINE AND RELATED NOVEL COMPOUNDS

摘要

The present invention relates to a process for preparing racemic narwedine (which can be can be kinetically resolved to yield (-)-narwedine and which is the biogenic precursor of (-)- galanthamine) and the use thereof as a starting material for producing (-)-galanthamine. The invention further includes processes for preparing (-)-galanthamine and (-)-galanthamine hydrobromide, as well as related novel compounds.