| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide new thalidomide derivative compounds having activity as anti-angiogenesis compounds. <P>SOLUTION: The compounds having the general structures have the anti-angiogenesis activity: wherein R<SB>1</SB>is selected from the group consisting of H, halo, alkyl, haloalkyl, -NH<SB>2</SB>, hydroxy and alkoxy; R<SB>2</SB>is selected from the group consisting of optionally substituted bicyclic, optionally substituted aryl, and R<SB>6</SB>is H, or 1-8C alkyl; R<SB>19</SB>is optionally substituted aryl; and m is 0-6. <P>COPYRIGHT: (C)2009,JPO&INPIT</p> |
