发明名称 Method of treating intraoccular tissue pathologies with nerve growth factor
摘要 Nerve Growth Factor (NGF), in the form of a preparation to be administered over ocular surface, is suggested as being suitable for therapy and/or prophylaxis of intraocular tissue pathologies, with particular reference to sclera, ciliary body, crystalline lens, retina, optic nerve, vitreous body and choroidea affections. When administered in the form of external ophthalmic preparation, for example as collyrium or ointment, NGF is capable to go through ocular tissues and it has been found out that it shows a therapeutic activity not only against retina and optic nerve pathologies but also against affections involving the above reported internal structures of the eye.
申请公布号 US9468665(B1) 申请公布日期 2016.10.18
申请号 US200009890088 申请日期 2000.01.21
申请人 Dompé Farmaceutici S.p.A. 发明人 Lambiase Alessandro
分类号 A61K38/18 主分类号 A61K38/18
代理机构 Fish & Richardson P.C. 代理人 Fish & Richardson P.C.
主权项 1. A method for treating glaucoma comprising: topically applying to an ocular surface of a human patient in need of such treatment an ophthalmic preparation comprising between about 10 μg/ml and about 500 μg/ml of nerve growth factor.
地址 Milan IT