| 发明名称 |
GENETIC POLYMORPHISMS ASSOCIATED WITH MYOCARDIAL INFARCTION, METHODS OF DETECTION AND USES THEREOF |
| 摘要 |
The present invention is based on the discovery of genetic polymorphisms that are associated with myocardial infarction. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection. |
| 申请公布号 |
US2016319352(A1) |
申请公布日期 |
2016.11.03 |
| 申请号 |
US201615058462 |
申请日期 |
2016.03.02 |
| 申请人 |
Celera Corporation |
发明人 |
IAKOUBOVA Olga;DEVLIN James J.;CARGILL Michele |
| 分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of determining whether a human has an altered risk for myocardial infarction, comprising testing nucleic acid from said human for the presence or absence of a polymorphism selected from the group consisting of the polymorphisms at position 101 of any one of the nucleotide sequences of SEQ ID NOS:18,017-73,085 or its complement, wherein the polymorphism indicates an altered risk for myocardial infarction. |
| 地址 |
San Clemente CA US |
