摘要 |
Sulfonyl derivatives represented by the following general formula (I): Q<1>-Q<2>-T<1>-Q<3>-SO2-Q<A> and drugs containing the same (wherein Q<1> is an optionally substituted, saturated or unsaturated, five- or six-membered cyclic hydrocarbon group, a five- or six-membered heterocyclic group, or the like; Q<2> is a single bond, oxygen, sulfur, C1-C6 alkylene or the like; Q<A> is optionally substituted arylalkenyl, heteroarylalkenyl or the like; and T<1> is carbonyl or the like). These compounds have potent FXa-inhibitory effects and promptly exert satisfactory and persistent antithrombotic effects through oral administration, thus being useful as anticoagulant agents little accompanied with side effects.
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申请人 |
DAIICHI PHARMACEUTICAL CO., LTD.;KOBAYASHI, SYOZO;KOMORIYA, SATOSHI;HAGINOYA, NORIYASU;SUZUKI, MASANORI;YOSHINO, TOSHIHARU;NAGAHARA, TAKAYASU;NAGATA, TSUTOMU;HORINO, HARUHIKO;ITO, MASAYUKI;MOCHIZUKI, AKIYOSHI |
发明人 |
KOBAYASHI, SYOZO;KOMORIYA, SATOSHI;HAGINOYA, NORIYASU;SUZUKI, MASANORI;YOSHINO, TOSHIHARU;NAGAHARA, TAKAYASU;NAGATA, TSUTOMU;HORINO, HARUHIKO;ITO, MASAYUKI;MOCHIZUKI, AKIYOSHI |