| 摘要 |
PURPOSE:To produce the subject compound useful as a dye, etc., under mild condition in high yield and purity without forming by-product by reacting nitrostyrenes with 1,3-propanediol, etc., in the presence of palladium chloride, etc., and oxygen gas and cyclizing the reaction product. CONSTITUTION:The objective indoles of formula III can be produced by reacting a compound of formula I (R is H, F, Cl, lower alkyl, lower alkoxy, etc.) with 1,3-propanediol or ethylene glycol in the presence of palladium chloride, cuprous chloride and oxygen-containing gas and cyclizing the resultant cyclic acetal compound of formula II (n is 2 or 3) under reducing condition. |
