Intrinsically anti-microbial copolymer, used e.g. as an in situ-produced coating on medical articles, is based on acryloyloxyalkylamino compound such as 2-dimethylaminoethyl methacrylate

摘要

An antimicrobial copolymer is made by copolymerization of an acryloyloxyalkylamino compound with an aliphatic unsaturated monomer. An antimicrobial copolymer is made by copolymerization of (A) an acryloyloxyalkylamino compound of formula (I) with (B) an aliphatic unsaturated monomer. R<1> = H or Me; R<2> = 1-5C hydrocarbon group; Y = NR<3>R<4> or NR<3>R<4>R<5>X<->; R<3>-R<5> = optionally substituted aliphatic or aromatic 1-50C hydrocarbon group; and X = (CH3SO4)<->, (NO3)<->, F<->, Cl<->, Br<->, I<->, (CH3CH2)<->, (NO2)<->, NO<->, CN<->, SCN<->, CNO<->, ClO<->, (ClO2)<->, (ClO3)<-> or (ClO4)<->.