发明名称 |
FILAMENTOUS BACTERIOPHAGE DISPLAYING PROTEIN AS A BINDER OF ANTIBODIES AND IMMUNOCOMPLEXES FOR DELIVERY TO THE BRAIN |
摘要 |
The present invention relates to a phage display vehicle composed of a filamentous bacteriophage displaying on its surface, as a non-filamentous bacteriophage molecule, protein A or a fragment or variant thereof capable of binding the Fc portion of antibodies, and an antibody or an antigen-antibody immunocomplex bound to protein A or a fragment or variant thereof by its Fc portion. The phage display vehicle is formulated into a pharmaceutical composition and can be used to treat/inhibit or to diagnose a brain disease, disorder or condition. |
申请公布号 |
WO2007095616(A3) |
申请公布日期 |
2007.12.13 |
申请号 |
WO2007US62238 |
申请日期 |
2007.02.15 |
申请人 |
RAMOT AT TEL AVIV UNIVERSITY;GERAGHTY, ERIN;SOLOMON, BEKA;COHEN KUPIEC, RACHEL |
发明人 |
SOLOMON, BEKA;COHEN KUPIEC, RACHEL |
分类号 |
A61K39/00;A61P3/06;C12N15/10 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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