发明名称 IMMUNOREGULATORY COMPOSITIONS COMPRISING HYDRALAZINE FOR TREATMENT OF GASTROINTESTINAL DISORDERS
摘要 PROBLEM TO BE SOLVED: To provide immunoregulatory preparations for use in the treatment of gastrointestinal disorders.SOLUTION: The invention relates to a hydroxylase inhibitor that is used in maintenance therapy of a patient suffering from inflammatory and/or fibrogenic intestinal disorders. The hydroxylase inhibitor is selected from DMOG, hydralazine, FG-4497, FG4095, and siRNAs against hydroxylases and antisense therapeutics against hydroxylases, e.g. against PHD1. Preferably, the hydroxylase inhibitor is hydralazine.SELECTED DRAWING: None
申请公布号 JP2016153419(A) 申请公布日期 2016.08.25
申请号 JP20160066903 申请日期 2016.03.29
申请人 SIGMOID PHARMA LTD 发明人 VINCENZO AVERSA;IVAN COULTER;MONICA TORRES ROSA;BERNARD FRANCIS MCDONALD
分类号 A61K45/00;A61K9/66;A61K31/436;A61K31/502;A61K31/706;A61K31/7105;A61K31/711;A61K38/00;A61K47/10;A61K47/12;A61K47/14;A61K47/20;A61K47/36;A61K47/38;A61K47/42;A61K47/44;A61K48/00;A61P1/04;A61P37/06;A61P43/00 主分类号 A61K45/00
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