发明名称 composto, pró-droga, agente farmacêutico, e, uso do composto
摘要 The present invention provides a compound represented by the formula: wherein R1a is a hydrogen atom, R2a is a C1-6 alkyl group substituted by a group represented by —NR6a—CO—(CH2)n—SO2— optionally halogenated C1-4 alkyl wherein n is an integer of 1 to 4, R6a is a hydrogen atom or a C1-4 alkyl group, and —(CH2)n— is optionally substituted by C1-4 alkyl, R3a is a hydrogen atom or a C1-6 alkyl group, R4a is a halogen atom or a C1-6 alkyl group, R5a is a halogen atom or a C1-6 alkyl group, and Xa is a hydrogen atom or a halogen atom, or a salt thereof. The compound of the present invention has a superior tyrosine kinase inhibitory action, is highly safe, and is sufficiently satisfactory as a pharmaceutical product.
申请公布号 BRPI0619911(A2) 申请公布日期 2016.08.30
申请号 BR2006PI19911 申请日期 2006.12.01
申请人 TAKEDA PHARMACEUTICAL COMPANY LIMITED 发明人 HIROSHI BANNO;KAZUHIRO MIWA;MASAKI SETO;TOMOYASU ISHIKAWA;YOUICHI KAWAKITA
分类号 C07D487/04;A61K31/519 主分类号 C07D487/04
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