摘要 |
Provided are pyrrolo[1,2-f][1,2,4]triazinyl, imidazo[1,5-f][1,2,4]triazinyl, imidazo[1,2-f][1,2,4]triazinyl, and [1,2,4]triazolo[4,3-f][1,2,4]triazinyl nucleosides of Formula (I), nucleoside phosphates and prodrugs thereof, wherein the l' position of the nucleoside sugar is substituted, and wherein each of X1 or X2 is independently C-R10 or N. The compounds, compositions, and methods provided may be useful for the treatment of Flaviviridae virus infections, particularly hepatitis C infections. (see formula I) |