发明名称 |
Polymer composition for controlled release of active ingredients in response to pH, and a process of preparing the same |
摘要 |
The present invention provides a polymer for the controlled release of a pendent chain linked active ingredient, and a process for the preparation of such a polymer for the controlled release of an active ingredient in response to pH. The process involves selecting a vinyl monomer to which the active ingredient molecule is covalently linked through a pendent group, and selecting monomers bearing catalytic groups. The active ingredient-bearing monomer and the catalytic group-containing monomer are brought in juxtaposition either by complexation or molecular imprinting, and then polymerized with a hydrophilic monomer and crosslinker under an inert atmosphere with a suitable polymerization initiator.
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申请公布号 |
US5851546(A) |
申请公布日期 |
1998.12.22 |
申请号 |
US19960615431 |
申请日期 |
1996.03.14 |
申请人 |
COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH |
发明人 |
MASHELKAR, RAGHUNATH ANANT;KULKARNI, MOHAN GOPALKRISHNA;KARMALKAR, ROHINI NITIN |
分类号 |
A01N25/10;A61K47/48;(IPC1-7):A61F2/00;A61K9/52 |
主分类号 |
A01N25/10 |
代理机构 |
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