| 发明名称 | Compositions and methods for treating obesity and obesity-related conditions | ||
| 摘要 | The present invention relates to the field of obesity. More specifically, the present invention provides methods and compositions useful in treating obesity and obesity-associated conditions. In one embodiment, a method for treating obesity in a subject comprises the step of administering an effective amount of valproic acid (VPA) or an analog, derivative or metabolite thereof to the subject. | ||
| 申请公布号 | US9463173(B2) | 申请公布日期 | 2016.10.11 |
| 申请号 | US201514637784 | 申请日期 | 2015.03.04 |
| 申请人 | THE JOHNS HOPKINS UNIVERSITY | 发明人 | Bumpus Namandje;Avery Lindsay |
| 分类号 | A01N37/00;A61K31/19 | 主分类号 | A01N37/00 |
| 代理机构 | Johns Hopkins Technology Transfer | 代理人 | Johns Hopkins Technology Transfer |
| 主权项 | 1. A method for reducing hepatic fat accumulation and serum glucose in a subject comprising the step of administering an effective amount of valproic acid (VPA) or metabolite thereof to the subject, wherein the VPA metabolite is one or more of 2-ene-VPA, 4-ene-VPA, 3-OH-VPA, and 3-keto-VPA. | ||
| 地址 | Baltimore MD US | ||