METHOD FOR DIAGNOSIS OF HEPATOCELLULAR CARCINOMA

摘要

The object is to provide a method for diagnosis of hepatocellular carcinoma and a method for detection of human a2,6-sialic acid transferase. Disclosed is a method for detection of human a2,6-sialic acid transferase, which comprises the step of conducting sandwich enzyme-linked immunosorbent assay (ELISA) by using a combination of an antibody capable of recognizing an amino acid sequence represented by the formula: Ser-Ser-Ala-Gly-Ser-Leu-Lys-Ser-Ser-Gln-Leu-Gly-Arg-Glu-Ile (SEQ ID NO:1) or the formula: Asn-Ser-Gln-Leu-Val- Thr-Thr-Glu-Lys-Arg-Phe-Leu-Lys-Asp-Ser-Leu (SEQ ID NO:2) included in the amino acid sequence for human a2,6-sialic acid transferase and an antibody capable of recognizing an amino acid sequence represented by the formula: Cys-Asp-Gln- Val-Asp-Ile-Tyr-Glu-Phe-Leu-Pro-Ser-Lys-Arg-Lys-Thr-Asp-Val (SEQ ID NO:3) included in the amino acid sequence for human a2,6-sialic acid transferase.