发明名称 Systems, Methods, and Compositions For Cross-Linking Treatments of an Eye
摘要 Systems, methods, and compositions generate cross-linking activity for treatment of eye disorders. Various agents, additives, buffers, etc., may be employed in formulations with a cross-linking agent to enhance treatment. For example, a composition for applying treatment to a cornea of an eye includes a cross-linking agent that generates cross-linking activity in the cornea in response to exposure to a photo-activating light. The composition also includes an iron additive and citrate buffer. In some cases, the cross-linking agent may include riboflavin. In other cases, the iron additive may include FeSO4. In further cases, the iron additive may be dissolved in the citrate buffer.
申请公布号 US2016175442(A1) 申请公布日期 2016.06.23
申请号 US201514957187 申请日期 2015.12.02
申请人 Avedro, Inc. 发明人 Kamaev Pavel;Friedman Marc;Sherr Evan;Peterson Sarah M.;Muller David
分类号 A61K41/00;A61N5/06;A61K47/12;A61K31/525;A61K47/02 主分类号 A61K41/00
代理机构 代理人
主权项 1. A composition for applying treatment to a cornea of an eye, comprising: a cross-linking agent that generates cross-linking activity in the cornea in response to exposure to a photo-activating light; an iron additive; and citrate buffer.
地址 Waltham MA US