发明名称 |
Systems, Methods, and Compositions For Cross-Linking Treatments of an Eye |
摘要 |
Systems, methods, and compositions generate cross-linking activity for treatment of eye disorders. Various agents, additives, buffers, etc., may be employed in formulations with a cross-linking agent to enhance treatment. For example, a composition for applying treatment to a cornea of an eye includes a cross-linking agent that generates cross-linking activity in the cornea in response to exposure to a photo-activating light. The composition also includes an iron additive and citrate buffer. In some cases, the cross-linking agent may include riboflavin. In other cases, the iron additive may include FeSO4. In further cases, the iron additive may be dissolved in the citrate buffer. |
申请公布号 |
US2016175442(A1) |
申请公布日期 |
2016.06.23 |
申请号 |
US201514957187 |
申请日期 |
2015.12.02 |
申请人 |
Avedro, Inc. |
发明人 |
Kamaev Pavel;Friedman Marc;Sherr Evan;Peterson Sarah M.;Muller David |
分类号 |
A61K41/00;A61N5/06;A61K47/12;A61K31/525;A61K47/02 |
主分类号 |
A61K41/00 |
代理机构 |
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代理人 |
|
主权项 |
1. A composition for applying treatment to a cornea of an eye, comprising:
a cross-linking agent that generates cross-linking activity in the cornea in response to exposure to a photo-activating light; an iron additive; and citrate buffer. |
地址 |
Waltham MA US |