IDENTIFICATION OF A CONSERVED INNER CORE OLIGOSACCHARIDE REGION OF MORAXELLA CATARRHALIS LIPOPOLYSACCHARIDE AS A VACCINE ANTIGEN

摘要

There are disclosed herein antigenic structures useful in producing vaccines against and compounds helpful in combating diseases caused by the bacterium Moraxella catarrhalis. Disclosed are specific structures of the carbohydrate molecules derived from genetically engineered strains of Moraxella catarrhalis, which when presented appropriately to the immune system will facilitate a functional immune response to the target core oligosaccharide region.