发明名称 |
COSMETIC PRESERVATIVES AS THERAPEUTIC CORNEOSCLERAL TISSUE CROSS-LINKING AGENTS |
摘要 |
A method of cross-linking collagen present in a collagenous tissue comprising contacting the collagenous tissue with an amount of a formaldehyde releasing agent effective to crosslink the collagen is provided. A method of inhibiting loss of structural integrity of a collagenous tissue during transplantation-related transport comprising contacting the collagenous tissue with an amount of a formaldehyde releasing agent effective to inhibit loss of structural integrity of the collagenous tissue is also provided. A composition for ophthalmic administration comprising a formaldehyde releasing agent, sodium bicarbonate, and ophthalmically suitable carriers or excipients is also provided. Finally, a method of altering the refractive power of a cornea comprising contacting the cornea with a formaldehyde releasing agent so as to effect cross-linking in the cornea and thereby alter the refractive power of the cornea is provided. |
申请公布号 |
US2016374992(A1) |
申请公布日期 |
2016.12.29 |
申请号 |
US201515125558 |
申请日期 |
2015.03.12 |
申请人 |
Paik David Choohyun;Trokel Stephen Lewis |
发明人 |
Paik David Choohyun;Trokel Stephen Lewis |
分类号 |
A61K31/4166 |
主分类号 |
A61K31/4166 |
代理机构 |
|
代理人 |
|
主权项 |
1. A method of cross-linking collagen present in a collagenous tissue comprising contacting the collagenous tissue with an amount of a formaldehyde releasing agent effective to cross-link the collagen. |
地址 |
Cheltenham PA US |