发明名称 |
METHOD AND DEVICE FOR MANUFACTURING POLYMER PARTICLES CONTAINING A THERAPEUTIC MATERIAL |
摘要 |
Methods and devices for manufacturing polymer particles containing a therapeutic material and polymer conjugate particles comprising (a) introducing a first stream comprising a first solvent into a channel, wherein the channel has a first region adapted for flowing one or more streams introduced into the channel and a second region for mixing the contents of the one or more streams; (b) introducing a second stream comprising polymer conjugate in a second solvent into the channel to provide first and second streams flowing in the channel; (c) flowing the one or more first streams and the one or more second streams from the first region of the channel into the second region of the channel; (d) mixing of the contents of the one or more first streams and the one or more second streams flowing in the second region of the channel to provide a third stream comprising polymer conjugate nanoparticles. |
申请公布号 |
US2016158383(A1) |
申请公布日期 |
2016.06.09 |
申请号 |
US201414907507 |
申请日期 |
2014.07.25 |
申请人 |
THE UNIVERSITY OF BRITISH COLUMBIA |
发明人 |
Ramsay Euan;Taylor Robert James;Wild Andre;Leaver Timothy;Walsh Colin |
分类号 |
A61K47/48;A61K31/337 |
主分类号 |
A61K47/48 |
代理机构 |
|
代理人 |
|
主权项 |
1. A method for making polymer conjugate nanoparticles, comprising:
(a) introducing a first stream comprising a first solvent into a channel, wherein the channel has a first region adapted for flowing one or more streams introduced into the channel and a second region for mixing the contents of the one or more streams; (b) introducing a second stream comprising polymer conjugate in a second solvent into the channel to provide first and second streams flowing in the channel; (c) flowing the one or more first streams and the one or more second streams from the first region of the channel into the second region of the channel; and (d) mixing of the contents of the one or more first streams and the one or more second streams flowing in the second region of the channel to provide a third stream comprising polymer conjugate nanoparticles. |
地址 |
Vancouver CA |