Hemodynamics-based monitoring and evaluation of a respiratory condition

摘要

Assessment of a respiratory condition of a subject, by acquiring a temporally varying hemodynamic waveform signal related to blood flow in a tissue; deriving from the hemodynamic waveform signal an evaluation of blood CO2; acquiring at least one more signal; and determining the medical condition based on the blood CO2 and the at least one more signal. A device for performing the assessment may include an implement disposable on the subject's skin and structured to acquire a temporally varying hemodynamic waveform signal and derive from the signal a blood CO2 value or a close approximation thereof; an oximeter disposable on the subject's skin and structured to provide an oxygen saturation value of the blood of the subject or a close approximation thereof; and an apparatus structured to evaluate the medical condition of the subject based on the blood CO2 and oxygen saturation or close approximations thereof.

主权项

1. A counter-implemented method for assessment of a respiratory condition of a subject, the method comprising:
(a) acquiring from the subject a temporally varying hemodynamic waveform signal related to blood flow in a tissue of the subject, and generating a representative cycle indicative of blood flow during a cardiac cycle therefrom; (b) deriving from the representative cycle an evaluation of blood carbon dioxide (CO2) of the subject by configuring a processing circuitry for:
generating a derivative cycle by computing a time derivative of the representative cycle;determining key points and features in the derivative cycle; anddetermining a CO2 level from the key points and features determined in the derivative cycle;wherein determining key points and features in the derivative cycle comprises determining a first point of maximum and determining a temporal distance between a first point and a second point; (c) acquiring from the subject at least one more signal relating to the respiratory or cardiovascular condition of the subject; and (d) determining the respiratory condition of the subject based on the blood CO2, the at least one more signal and a relationship between the blood CO2 and the at least one more signal.