发明名称 |
HETEROARYLOXY-BETA-CARBOLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINAL AGENTS |
摘要 |
Heteroaryloxy-.beta.-carboline derivatives of general Formula I (I), wherein R1 is an optionally substituted heteroaryl residue, R2 is hydrogen, lower alkyl or lower alkoxyalkyl, X is a COOR3-group wherein R3 means H or lower alkyl, or represents a CONR4R5-group wherein R4 and R5 mean respectively hydrogen or lower alkyl, R4 and R5 being capable of forming, together with the nitrogen atom, a 5- -to 6-membered heterocycle, or means an oxadiazolyl residue of the formula or wherein R6 means hydrogen, lower alkyl or cycloalkyl, are valuable pharmaceuticals. |
申请公布号 |
CA1315784(C) |
申请公布日期 |
1993.04.06 |
申请号 |
CA19870531388 |
申请日期 |
1987.03.06 |
申请人 |
BIERE, HELMUT |
发明人 |
BIERE, HELMUT;HUTH, ANDREAS;RAHTZ, DIETER;SCHMIECHEN, RALPH;SEIDELMANN, DIETER;STEPHENS, DAVID N.;ENGELSTOFT, MOGENS;HANSEN, JOHN B. |
分类号 |
A61K31/435;A61K31/495;A61K31/505;A61P25/00;A61P25/08;A61P25/20;A61P25/28;C07D471/04 |
主分类号 |
A61K31/435 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|