FAB FRAGMENT LIBRARIES AND METHODS FOR THEIR USE

摘要

The present invention provides Fab libraries and methods for using the Fab libraries to obtain antibodies against a target. The Fab library of the invention contains at least 10 9 different Fabs, and in some embodiments, at least 10 10 different Fabs. The Fab libraries of the invention are used to isolate polyclonal or monoclonal Fabs that bind with high specificity to targets.