| 摘要 |
This invention presents a novel protein consisting essentially of purified retinal pigment epithelial protective protein (RPP) or purified biologically active variants thereof, or immunogenic fragments or a combination of purified retinal pigment epithelial protective protein and biologically active variants thereof. Also presented are methods and kits for detecting a protein capable of inhibiting neutrophil activation in inflammatory conditions, by detecting the presence of these proteins, their immunogenic fragments, antibodies to these proteins or their fragments, or polynucleotides which encode or are translatable into these proteins or their fragments. Further disclosed are methods for isolating these proteins. Still further disclosed are methods for treating diseases associated with tissue damage due to oxygen metabolite production.
|
