DNA segments encoding two slightly different protease nexin I forms (PN-I alpha and PN-I beta ) are cloned and expressed to provide practical quantities of PN-I for diagnostic and therapeutic use. PN-I is a serine protease inhibitor useful in controlling conditions mediated by proteolytic activity.
申请公布号
US5495001(A)
申请公布日期
1996.02.27
申请号
US19940288596
申请日期
1994.08.10
申请人
INCYTE PHARMACEUTICALS, INC.
发明人
MCGROGAN, MICHAEL P.;SCOTT, RANDY W.;BAKER, JOFFRE B.;SIMONSEN, SR., CHRISTIAN C.