发明名称 TRANS-2-DECENOIC ACID DERIVATIVE AND DRUG CONTAINING SAME
摘要 The present invention pertains to: a novel trans-2-decenoic acid derivative or a pharmaceutically acceptable salt thereof; and a drug containing the compound as the active ingredient. Specifically, the trans-2-decenoic acid derivative or a pharmaceutically acceptable salt thereof is represented by general formula (I) (in the formula, X indicates a substituent group such as 1-pyrrolidilyl, 3-thiazolidyl, or piperidino), and is highly useful as a drug such as a prevention or treatment agent for peripheral nerve disorders resulting from anti-cancer drug administration, a prevention or treatment agent for neurodegenerative disorders or psychiatric disorders including dementia, Alzheimer's disease, Parkinson's disease, diabetic neuropathy, depression, glaucoma, and autism spectrum disorders, a treatment or repair agent for spinal injuries, an analgesic for various pain disorders, and the like.
申请公布号 CA2870822(C) 申请公布日期 2016.06.21
申请号 CA20132870822 申请日期 2013.04.26
申请人 NIPPON ZOKI PHARMACEUTICAL CO., LTD.;NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE 发明人 IINUMA, MUNEKAZU;FURUKAWA, SHOEI;NAIKI, MITSURU;MATSUMOTO, TOMONORI;HIGASHIURA, KUNIHIKO
分类号 C07D207/16;A61K9/70;A61K31/40;A61K31/401;A61K31/426;A61K31/445;A61K31/4453;A61K31/495;A61K31/496;A61K31/506;A61K31/5375;A61K31/54;A61K31/55;A61K31/551;A61K47/40;A61P19/02;A61P25/00;A61P25/02;A61P25/04;A61P25/16;A61P25/22;A61P25/24;A61P25/28;A61P27/06;C07D211/16;C07D211/18;C07D211/26;C07D211/30;C07D211/44;C07D211/46;C07D211/48;C07D211/58;C07D211/62;C07D213/74;C07D239/42;C07D243/08;C07D277/04;C07D295/18 主分类号 C07D207/16
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