发明名称 |
TRICYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE |
摘要 |
The present invention relates to novel tricyclic compounds which can bind to FXR and act as modulators of the FXR, or a stereoisomer, a geometric isomer, a tautomer, an N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, and the uses of the compounds for the treatment of diseases and/or conditions mediated by FXR. The invention further provides a pharmaceutical composition containing the compound disclosed herein and a method of treatment of diseases and/or conditions mediated by FXR comprising administering the compound or the pharmaceutical composition. |
申请公布号 |
WO2016127924(A1) |
申请公布日期 |
2016.08.18 |
申请号 |
WO2016CN73617 |
申请日期 |
2016.02.05 |
申请人 |
SUNSHINE LAKE PHARMA CO., LTD. |
发明人 |
WANG, Xiaojun;YANG, Xinye;PAN, Shengqiang;GUO, Rui;WU, Junwen;ZHANG, Yingjun;CHENG, Changchung |
分类号 |
C07D413/12;A61K31/42;A61K31/4353;A61K31/4985;A61K31/519;C07D261/08;C07D411/12;C07D471/04;C07D491/044;C07D497/04;C07D498/14 |
主分类号 |
C07D413/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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