POLYMORPHS OF 2-(4-(2-(1-ISOPROPYL-3-METHYL-1H-1,2,4-TRIAZOL-5-YL )-5,6-DIHYDROBENZO[F]IMIDAZO[1,2-D][1,4]OXAZEPIN-9-YL)-1H-PYRAZO L-1-YL)-2-METHYLPROPANAMIDE, METHODS OF PRODUCTION, AND PHARMACEUTICAL USES THEREOF.

摘要

The present invention relates to crystalline polymorphs of (2-(4-(2-(1-isopropyl-3-methyl-1H-,2,4-triazol-5-yl)-5,6-dihydr obenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)-1H-pyrazol-1-yl)-2- methylpropanamide (GDC-0032, taselisib), methods of use, and processes of preparing thereof.