| 发明名称 | Modified polynucleotides for the production of nuclear proteins | ||
| 摘要 | The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules. | ||
| 申请公布号 | US9504734(B2) | 申请公布日期 | 2016.11.29 |
| 申请号 | US201514975141 | 申请日期 | 2015.12.18 |
| 申请人 | ModernaTX, Inc. | 发明人 | Bancel Stephane;Chakraborty Tirtha;de Fougerolles Antonin;Elbashir Sayda M.;John Matthias;Roy Atanu;Whoriskey Susan;Wood Kristy M.;Hatala Paul;Schrum Jason P.;Ejebe Kenechi;Ellsworth Jeff Lynn;Guild Justin;Weiss Ron |
| 分类号 | C12N15/85;A61K38/48;A61K48/00;C12N15/88;A61K9/127;A61K9/50;A61K31/7088;A61K47/48;C07K19/00;A61K38/18;A61K38/19;C07K14/47;A61K9/00 | 主分类号 | C12N15/85 |
| 代理机构 | Clark & Elbing LLP | 代理人 | Clark & Elbing LLP |
| 主权项 | 1. An mRNA encoding SEQ ID NO: 7559, wherein said mRNA comprises a coding region having at least 80% identity to SEQ ID NO: 14963. | ||
| 地址 | Cambridge MA US | ||