发明名称 |
DERIVATIVES OF PIPERAZINE-2,5-DIONE AS MULTIDRUG RESISTANCE MODULATORS |
摘要 |
<p>PCT No. PCT/GB95/03029 Sec. 371 Date Aug. 29, 1997 Sec. 102(e) Date Aug. 29, 1997 PCT Filed Dec. 22, 1995 PCT Pub. No. WO96/20180 PCT Pub. Date Jul. 4, 1996A piperazinedione of general formula (I): wherein R1 is selected from hydrogen; a group of formula -(NH)t-COR3 wherein t is 0 or 1 and R3 is an organic substituent as defined herein; a group of formula (D): and a group of formula (E): and the pharmaceutically acceptable salts thereof are useful as modulators of multi-drug resistance.</p> |
申请公布号 |
CZ9701902(A3) |
申请公布日期 |
1998.01.14 |
申请号 |
CZ19970001902 |
申请日期 |
1995.12.22 |
申请人 |
XENOVA LIMITED |
发明人 |
ASHWORTH PHILIP ANTHONY;HUNJAN SUKHJIT;PRETSWELL IAN ANDREW;RYDER HAMISH;BROCCHINI STEPHEN JAMES |
分类号 |
A61K31/495;A61P31/12;A61P35/00;C07D241/02;C07D401/10;C07D401/12;C07D471/04;(IPC1-7):C07D241/02 |
主分类号 |
A61K31/495 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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