发明名称 Method for purification of acarbose
摘要 The present invention relates to a novel process for the preparation of acarbose. Said process comprises the steps of: 1) acidifying a fermentation broth containing an acarbose; 2) removing particulates from the fermentation broth; 3) adsorbing the acarbose on a cation-exchanger in the presence of an anion of a weak acid; 4) eluting the acarbose from the cation-exchanger with at least one of hydrochloric acid and the weak acid; 5) precipitating the acarbose with a solvent; and 6) separating the acarbose.
申请公布号 US2002111320(A1) 申请公布日期 2002.08.15
申请号 US20010924271 申请日期 2001.08.07
申请人 KERI VILMOS;DEAK LAJOS 发明人 KERI VILMOS;DEAK LAJOS
分类号 C07H1/08;C07H15/203;C07H17/08;(IPC1-7):A61K31/703;C07H5/04 主分类号 C07H1/08
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