发明名称 Process for obtaining immunoglobulins from colostral milk
摘要 Suggested is a process for obtaining immunoglobulins, wherein (a) colostral milk from days 0 to 7 is subjected to thermal treatment, skimming the cream,(b) the skimmed milk such obtained is subjected to sterile microfiltration thus producing a first retentate R1 which contains the casein, and a first permeate P1,(c) the first permeate P1 is subjected to ultrafiltration thus producing a second permeate P2 which contains lactose and minerals, and a second retentate R2, in which the immunoglobulins are concentrated.
申请公布号 US9475860(B2) 申请公布日期 2016.10.25
申请号 US201414168586 申请日期 2014.01.30
申请人 DMK Deutsches Milchkontor GmbH 发明人 Döring Sven-Rainer
分类号 C07K16/04;A23C9/142;A23J3/08;A23C9/20 主分类号 C07K16/04
代理机构 Dilworth & Barrese, LLP 代理人 Dilworth & Barrese, LLP
主权项 1. A process for obtaining immunoglobulins consisting essentially of: (a) colostral milk from days 0to 7is subjected to thermal treatment, skimming the cream, (b) the skimmed milk such obtained is subjected at a temperature of from about 50 to about 70° C. to a sterile microfiltration thus producing a first retentate R1 which contains the casein, and a first permeate P1, (c) the first permeate P1 is subjected at a temperature of from about 5 to about 15° C. to ultrafiltration thus producing a second permeate P2 which contains lactose and minerals, and a second retentate R2, in which the immunoglobulins are concentrated, and (d) the immunoglobulins thus obtained from the second retentate are separated off from by treatment with anion exchanger.
地址 Zeven DE