发明名称 |
Process for obtaining immunoglobulins from colostral milk |
摘要 |
Suggested is a process for obtaining immunoglobulins, wherein
(a) colostral milk from days 0 to 7 is subjected to thermal treatment, skimming the cream,(b) the skimmed milk such obtained is subjected to sterile microfiltration thus producing a first retentate R1 which contains the casein, and a first permeate P1,(c) the first permeate P1 is subjected to ultrafiltration thus producing a second permeate P2 which contains lactose and minerals, and a second retentate R2, in which the immunoglobulins are concentrated. |
申请公布号 |
US9475860(B2) |
申请公布日期 |
2016.10.25 |
申请号 |
US201414168586 |
申请日期 |
2014.01.30 |
申请人 |
DMK Deutsches Milchkontor GmbH |
发明人 |
Döring Sven-Rainer |
分类号 |
C07K16/04;A23C9/142;A23J3/08;A23C9/20 |
主分类号 |
C07K16/04 |
代理机构 |
Dilworth & Barrese, LLP |
代理人 |
Dilworth & Barrese, LLP |
主权项 |
1. A process for obtaining immunoglobulins consisting essentially of:
(a) colostral milk from days 0to 7is subjected to thermal treatment, skimming the cream, (b) the skimmed milk such obtained is subjected at a temperature of from about 50 to about 70° C. to a sterile microfiltration thus producing a first retentate R1 which contains the casein, and a first permeate P1, (c) the first permeate P1 is subjected at a temperature of from about 5 to about 15° C. to ultrafiltration thus producing a second permeate P2 which contains lactose and minerals, and a second retentate R2, in which the immunoglobulins are concentrated, and (d) the immunoglobulins thus obtained from the second retentate are separated off from by treatment with anion exchanger. |
地址 |
Zeven DE |