| 发明名称 |
Human platelet-derived growth factor receptor extracellular domain antibodies |
| 摘要 |
This invention provides antibodies that bind to epitopes of human platelet-derived growth factor receptor (hPDGF-R) fragments, wherein the fragments comprise one or more platelet-derived growth factor (PDGF) ligand binding regions from extracellular domains D1, D2, and D3. Also provided are antibodies specific for domain D3, such as monoclonal antibodies directed to the intra-cysteine portion of domain D3.
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| 申请公布号 |
US5872218(A) |
申请公布日期 |
1999.02.16 |
| 申请号 |
US19950460510 |
申请日期 |
1995.06.02 |
| 申请人 |
COR THERAPEUTICS, INC.;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
WOLF, DAVID;TOMLINSON, JAMES E.;FRETTO, LARRY J.;GIESE, NEILL A.;ESCOBEDO, JAIME A.;WILLIAMS, LEWIS THOMAS |
| 分类号 |
A61K39/395;A61K38/00;C07K7/04;C07K14/00;C07K14/705;C07K14/71;C07K16/00;C07K16/28;C12N5/10;C12N15/02;C12N15/09;C12N15/12;C12P21/02;C12P21/08;C12R1/91;G01N33/53;G01N33/566;(IPC1-7):C07K16/28 |
主分类号 |
A61K39/395 |
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