发明名称 COMBINATION THERAPY USING COX-2 SELECTIVE INHIBITOR AND THROMBOXANE INHIBITOR AND COMPOSITIONS THEREFOR
摘要 The present invention provides a method for the treatment or prophylaxis of COX-2 mediated conditions in patients who are at risk of developing thromboembolic events which comprises administering to said patient a therapeutically or prophylactically effective amount of a COX-2 selective inhibitor and a cardiovascular protective amount of a thromboxane inhibitor, as well as compositions therefor.
申请公布号 CA2407469(A1) 申请公布日期 2001.11.22
申请号 CA20012407469 申请日期 2001.05.14
申请人 MERCK FROSST CANADA & CO. 发明人 SCOLNICK, EDWARD;TURNER, MERVYN;RIENDEAU, DENIS;METTERS, KATHLEEN
分类号 C07D231/12;A61K31/122;A61K31/365;A61K31/415;A61K31/42;A61K31/427;A61K31/444;A61K45/06;A61P1/02;A61P7/02;A61P9/00;A61P9/10;A61P11/00;A61P15/08;A61P17/02;A61P19/00;A61P19/02;A61P19/06;A61P21/00;A61P25/02;A61P25/04;A61P25/06;A61P25/28;A61P29/00;A61P31/12;A61P31/16;A61P35/00;A61P43/00;C07D213/61;C07D261/08;C07D307/58;(IPC1-7):A61K45/06 主分类号 C07D231/12
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