| 摘要 |
A process for preparing (+)-homopilopic acid and the salts thereof which comprises hydrolyzing a mixture of (+)-homopilopic acid ester of the general formula(I): wherein R1 denotes straight or branched C1-C10 hydrocarbon, and (-)-homopilopic acid ester of the general formula(II): wherein R2 denotes straight or branched C1-C10 hydrocarbon, in the presence of a microorganism belonging to the genus Arthrobacter, Aspergillus, Escherichia, Cunninghamella, Xanthomonas, Candida, Pseudomonas, Serratia, Cellulomonas, Nocardia, Bacillus, Brevibacterium, Flavobacterium, Mycobacterium, Rhizomucor, Rhodotorula or Rhodococcus, or an enzyme composition extracted or disrupted from these microorganisms.
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