VOLUME REDUCTION FILTRATION DEVICES FOR CELL SUSPENSION AND METHOD

摘要

The present invention provides devices, apparatus and systems suitable for achieving volume reduction in a liquid containing a species in suspension and methods of use thereof. The apparatus of the invention comprises (i) a filter device comprising: a tubular first chamber having a filter provided in a surface thereof, a second chamber in fluid communication with the first chamber through the filter, the device being provided with an inlet port opening to the first end of the first chamber, an outlet port opening to the second end of the first chamber, and a filtrate port opening to the second chamber, and (ii) a fluidic pathway from the outlet port, wherein the apparatus is configured to introduce the first liquid and a second fluid immiscible with the first to the first chamber and the apparatus comprises a flow cut-off means in the fluidic pathway from the outlet port.