| 发明名称 |
IMMUNOMODULATING COMPOSITIONS AND METHODS OF USE THEREOF |
| 摘要 |
This invention is directed to β-1-6-glucans, compositions and devices comprising the same, and methods of use thereof in modulating immune responses. The β-1-6-glucans of certain embodiments of the invention are enriched for O-acetylated groups and/or conjugated to a solid support or linked to a targeting moiety. |
| 申请公布号 |
US2016331774(A1) |
申请公布日期 |
2016.11.17 |
| 申请号 |
US201615220153 |
申请日期 |
2016.07.26 |
| 申请人 |
Whitehead Institute ;Massachusetts Institute of Technology ;Trustees of Boston University ;The General Hospital Corporation d/b/a Massachusetts General Hospital |
发明人 |
Rubin-Bejerano Ifat;Fink Gerald R.;Abeijon Claudia;Kohane Daniel S.;Fuller Jason E.;Langer Robert S. |
| 分类号 |
A61K31/716;A61K39/35;A61K39/00;A61K47/48;A61K39/39;A61L31/16;A61K45/06;A61K36/064;A61K36/09;A61K9/16 |
主分类号 |
A61K31/716 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition comprising β-1-6-glucan enriched for O-acetylated groups. |
| 地址 |
Cambridge MA US |
