发明名称 NOVEL PYRROLO [3,2-D] PYRIMIDIN-4-ONE DERIVATIVES AND THEIR USE IN THERAPY
摘要 There are disclosed novel compounds of formula (I) wherein R1, R12, L, X and Y are as defined in the specification, and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of the enzyme MPO and are thereby particularly useful in the treatment or prophylaxis of neuroinflammatory disorders, cardiovascular disorders and respiratory disorders.
申请公布号 IL183182(D0) 申请公布日期 2007.09.20
申请号 IL20070183182 申请日期 2007.05.14
申请人 ASTRAZENECA AB;TIDEN, ANNA-KARIN;BOGEVIG, ANDERS;LO-ALFREDSSON, YVONNE;PIVONKA, DONALD 发明人
分类号 C07D 主分类号 C07D
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