| 发明名称 |
ANTIBODY AND UTILIZATION THEREOF |
| 摘要 |
An antibody binding to a complex of osteoclastogenesis inhibitory factor (OCIF) with soluble OCIF-binding molecule (sOBM), i.e., OCIF/sOBM complex occurring in bodily fluids; hybridomas producing this antibody; and preventives or remedies for bone metabolic errors containing this antibody as the active ingredient. A method for diagnosing bone metabolic errors, in particular, rheumatoid arthritis which comprises quantifying the OCIF/sOMB complex; and a kit for diagnosing bone metabolic errors. This antibody is useful in diagnosing, preventing or treating bone metabolic errors, in particular, joint diseases such as rheumatoid arthritis or in analytical reagents for laboratory use, etc.
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| 申请公布号 |
WO02062990(A1) |
申请公布日期 |
2002.08.15 |
| 申请号 |
WO2002JP00963 |
申请日期 |
2002.02.06 |
| 申请人 |
SANKYO COMPANY, LIMITED;WASHIDA, NAOHIRO;SATAKE, TOSHIKO;YANO, KAZUKI |
发明人 |
WASHIDA, NAOHIRO;SATAKE, TOSHIKO;YANO, KAZUKI |
| 分类号 |
A61P19/08;A61P19/10;C07K16/28;C12P21/08;G01N33/566;G01N33/68;(IPC1-7):C12N15/02;C12N5/10;C07K16/24;A61K39/395;G01N33/53;G01N33/577;C07K14/51 |
主分类号 |
A61P19/08 |
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