Controlled release carbonic anhydrase inhibitor containing pharmaceutical compositions from spherical granules in capsule oral dosage unit form.

摘要

A controlled release pharmaceutical composition in oral dose unit form comprising a hard or soft shell capsule containing a filling comprising a therapeutically effective number of active spherical granules comprising an effective amount of at least one carbonic anhydrase inhibitor active medicament, a pharmaceutically acceptable normally solid diluent adapted to form a diffusable matrix for the carbonic anhydrase inhibitor active medicament and an optional pharmaceutically acceptable excipient. A method for the preparation and for the administration of the above defined composition is provided as well.