| 摘要 |
Genome DNA and cDNA encoding .DELTA.9-desaturase derived from a microorganism belonging to Mortierella s.p. mortierella, an expression vector and a transformant for expressing the same, and a process for preparing .DELTA.9desaturase using a gene encoding the enzyme. Introduction of the .DELTA.9desaturase gene into cells capable of producing an unsaturated fatty acid can enhance the conversion to palmitoleic acid and oleic acid as starting compounds of unsaturated fatty acids, resulting in improved productivity of the unsaturated fatty acids. When a cytochrome b5 gene or a cytochrome b5 reductase gene, i.e., a constituent of a microsomal electron transport system, is combined with the .DELTA.9-desaturase, more efficient production can be expected. Further, the .DELTA.9-desaturase can be efficiently produced by a recombinant DNA method. |
