发明名称 PYRIDIC KETONE DERIVATIVES, METHOD OF PREPARING SAME, AND PHARMACEUTICAL APPLICATION THEREOF
摘要 The present invention relates to pyridic ketone derivatives, method of preparing same, and pharmaceutical application thereof. Specifically, the present invention relates to pyridic ketone derivatives represented by a general formula (I) and pharmaceutical salts thereof, method of preparing same, and use thereof as MEK inhibitors and especially as therapeutic agents for cancer, where the definitions of the substituents in the general formula (I) are the same as the definitions in the specification.
申请公布号 EP3061747(A1) 申请公布日期 2016.08.31
申请号 EP20140854930 申请日期 2014.09.05
申请人 SHANGHAI HENGRUI PHARMACEUTICAL CO. LTD.;JIANGSU HENGRUI MEDICINE CO. LTD. 发明人 TU, WANGYANG;ZHANG, HAITANG;XU, GUOJI;CHI, JIANGTAO
分类号 C07D213/82;A61K31/4412;A61K31/443;A61K31/444;A61K31/519;A61P9/00;A61P29/00;A61P35/00;A61P37/02;C07D405/12;C07D471/04 主分类号 C07D213/82
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