发明名称 Salts of aza-bicyclic di-aryl ethers and pharmaceuticals thereof
摘要 The present invention relates to salts of (R)-3-(6-(4-methylphenyl)-pyridin-3-yloxy)-1-aza-bicyclo[2.2.2]octane, to methods for making them or their precursors, to pharmaceutical compositions comprising them, and to their use as medicaments.
申请公布号 US9365565(B2) 申请公布日期 2016.06.14
申请号 US201214232717 申请日期 2012.07.12
申请人 Novartis AG 发明人 Marterer Wolfgang;Prashad Mahavir;Villhauer Edwin Bernard;Waykole Liladhar Murlidhar;Vivelo James Anthony;Sutter Bertrand;Bianchi Jean-Claude;Wu Raeann;Har Denis;Karpinski Piotr H.;Pignone Massimo;Stingelin Doris;Buerger Eckart
分类号 A61K9/20;C07D453/02;A61K31/194;A61K31/439;C07C55/08;C07C55/10;C07C57/145;C07C57/15 主分类号 A61K9/20
代理机构 Hoffman Warnick LLC 代理人 Hoffman Warnick LLC
主权项 1. A pharmaceutical composition, which comprises a salt of (R)-3-(6-(4-methylphenyl)-pyridin-3-yloxy)-1-aza-bicyclo[2.2.2]octane, wherein said salt is the fumarate, maleate, chloride, phosphate, succinate or malonate salt of (R)-3-(6-(4-methylphenyl)-pyridin-3-yloxy)-1-aza-bicyclo[2.2.2]octane as active ingredient; and at least one pharmaceutically acceptable carrier.
地址 Basel CH