发明名称 PHARMACEUTICAL COMPOSITIONS COMPRISING SODIUM META ARSENITE FOR TREATMENT OF MULTIPLE MYELOMA
摘要 The present application relates to pharmaceutical compositions and methods for treatment of urogenital diseases and bone metastasis in a human, which pharmaceutical composition contains an effective amount of arsenous acid alkaline or earth alkaline metal salt and/or a pharmaceutically acceptable adjuvant. According to the present invention, the alkaline arsenous acid metal salt is sodium meta-arsenita (AsO2Na) or potassium meta-arsenite (AsO2K). The effective amount of arsenous acid alkaline or earth alkaline metal salt is 0.0001-1500 mg/kg, preferably 1-1000 mg/kg, more preferably 1-150 mg/kg, and most preferably 50-100 mg/kg of body weight/day. The administration form of the pharmaceutical compositions of the invention is preferably oral, such as a tablet, capsule, powder and/or solution with a pharmaceutically acceptable carrier, diluent or excipient.
申请公布号 US2016199411(A1) 申请公布日期 2016.07.14
申请号 US201615077373 申请日期 2016.03.22
申请人 KOMINOX, INC. 发明人 RADEMAKER Bernardus
分类号 A61K33/36;A61K45/06 主分类号 A61K33/36
代理机构 代理人
主权项 1. A method of treating multiple myeloma in a patient comprising administering a composition comprising a therapeutically effective amount of sodium meta arsenite to the patient.
地址 GEORGE TOWN KY