<p>A granular material which has a mean particle diameter of 150 to 800 micrometers; and an unsettled bulk density of 0.1 to 0.35 g/cm3 and/or a compactibility which results in a compact with a tensile strength of at least 1.7 MPa when the granular material is subjected to a compaction pressure of 266 MPa; and wherein the main component of the granular material is a cellulose derivative or an alkylene oxide homo- or copolymer or a blend thereof is useful for preparing dosage forms with a controlled release profile.</p>
申请公布号
EP2146696(A2)
申请公布日期
2010.01.27
申请号
EP20080730949
申请日期
2008.02.28
申请人
DOW GLOBAL TECHNOLOGIES INC.
发明人
CABELKA, TIM, D.;BELLARE, AKSHAY;CHAN, KA CHUN, A.;DASBACH, TINA, P.;ENDER, KACEE, B.;JACOB, KARL, V.;SCHEID, ROBERT, E.