| 发明名称 |
Immunostimulatory oligodeoxynucleotides |
| 摘要 |
The present invention relates to immunostimulatory oligodeoxynucleotides, vectors and vaccines comprising such oligodeoxynucleotides, to their use as a medicament, to their use in preventing or combating infectious disease, to methods for the detection of such oligodeoxynucleotides and to cells to be used in these method. |
| 申请公布号 |
US9364531(B2) |
申请公布日期 |
2016.06.14 |
| 申请号 |
US201113976121 |
申请日期 |
2011.12.29 |
| 申请人 |
Intervet Inc. |
发明人 |
Schrier Carla Christina;Ilg Thomas Simon |
| 分类号 |
A61K39/17;A61K39/12;C12N15/117;A61K39/39;A61K39/00 |
主分类号 |
A61K39/17 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An immunostimulatory non-methylated oligodeoxynucleotide having the general formula
5′[N1]x[N7]r{N3[N4]pC G[N5]qN6}n[N8]s[N2]z3′ wherein N1 is G; N2 is G; N3=T; Each N4 and N5 are T; N6=A, T or C; N7=G; N8=G; x=3-10; z=0-10; n=3-10; p=1-25; q=1-25; r=0-8; s=0-8; or a pharmaceutically acceptable salt thereof. |
| 地址 |
Madison NJ US |
